Dr Giles joined CiiiD in February 2016 as a clinician-scientist and performs research on the mucosal immunology of inflammatory bowel diseases (IBD), particularly the role of type I interferons and their influence on the adaptive immune system and microbiome of the intestine.
At the same time, Dr Giles has an appointment as a Consultant Paediatric Gastroenterologist at the Monash Children’s Hospital of the Monash Health network, where he is lead for paediatric IBD and has established a specific clinic for young adult patients with inflammatory bowel diseases in close collaboration with Dr Greg Moore, head of adult IBD at Monash Health. This is a unique clinical service in Victoria and is modelled on a clinic Dr Giles ran jointly in the UK.
He is a Fellow of the Royal Australasian College of Physicians and was awarded his PhD on Type I Interferon Signaling in human intestinal T Cells from the University of London in 2015. In 2017, he was appointed to the Gastroenterological Society of Australia (GESA) research committee.
Giles EM, Sanders TJ, McCarthy NE, Pathak, M, Lung, J, MacDonald TT, Lindsay JO, Stagg AJ (2016) Regulation of human intestinal T-cell responses by Type 1 Interferon-STAT1 signalling is disrupted in inflammatory bowel disease. Mucosal Immunology 10(1):184-193.
Giles EM, Croft NM (2016) Esophageal and gastric disorders in infancy and childhood. In Autoimmune Gastropathy. Till, H et al., eds. Heidelberg, Germany: Springer-Verlag Berlin 1417-1423.
Giles E, Hanci O, McLean A, Power N, Cole A, Croft NM, McDonald K, Chippington S, Naik S (2012) Optimal assessment of paediatric IBD – A comparison study of MRI and Barium Follow Through. Journal of Pediatric Gastroenterology and Nutrition 54(6):758–762.
Giles E, Barclay AR, Chippington S, Wilson DC (2013) Systematic review: MRI enterography for assessment of small bowel involvement in paediatric Crohn’s disease. Alimentary Pharmacology and Therapeutics 37(12): 121–1131.