Dr Edward Giles, M.B.B.S, PhD

Dr Giles joined CiiiD in February 2016 as a clinician-scientist and performs research on the mucosal immunology of inflammatory bowel diseases (IBD), particularly the role of type I interferons and their influence on the adaptive immune system and microbiome of the intestine.

At the same time, Dr Giles has an appointment as a Consultant Paediatric Gastroenterologist at the Monash Children’s Hospital of the Monash Health network, where he is lead for paediatric IBD and has established a specific clinic for young adult patients with inflammatory bowel diseases in close collaboration with Dr Greg Moore, head of adult IBD at Monash Health. This is a unique clinical service in Victoria and is modelled on a clinic Dr Giles ran jointly in the UK.

He is a Fellow of the Royal Australasian College of Physicians and was awarded his PhD on Type I Interferon Signaling in human intestinal T Cells from the University of London in 2015. In 2017, he was appointed to the Gastroenterological Society of Australia (GESA) research committee.

Selected publications

  • Giles EM, Sanders TJ, McCarthy NE, Pathak, M, Lung, J, MacDonald TT, Lindsay JO, Stagg AJ (2016) Regulation of human intestinal T-cell responses by Type 1 Interferon-STAT1 signalling is disrupted in inflammatory bowel disease. Mucosal Immunology 10(1):184-193.

  • Giles EM, Croft NM (2016) Esophageal and gastric disorders in infancy and childhood. In Autoimmune Gastropathy.  Till, H et al., eds. Heidelberg, Germany: Springer-Verlag Berlin 1417-1423.

     

  • Giles E, Hanci O, McLean A, Power N, Cole A, Croft NM, McDonald K, Chippington S, Naik S (2012) Optimal assessment of paediatric IBD – A comparison study of MRI and Barium Follow Through. Journal of Pediatric Gastroenterology and Nutrition 54(6):758–762.

  • Giles E, Barclay AR, Chippington S, Wilson DC (2013) Systematic review: MRI enterography for assessment of small bowel involvement in paediatric Crohn’s disease. Alimentary Pharmacology and Therapeutics 37(12): 121–1131.