Project description

Exposure to infection/inflammation during the perinatal period is one of the main causes of impaired neurodevelopment. To develop effective therapeutic interventions against perinatal infection/inflammation we must first understand the pathophysiology of inflammation induced brain remodelling. This project integrates techniques in immunology, physiology, microbiology and neuroscience to develop a clinically relevant model that will advance our understanding of how infection/inflammation alters structural and functional development of the perinatal brain.