ARC Discovery Project Grant

This project will study a key molecular switch required for cells and organs to form and function normally, and reveal how it works. The work will provide the first complete description of how this molecular switch controls the behaviour of a cell across its lifespan.  The new knowledge will reveal how this switch controls the formation of sperm by revealing what other proteins it binds to and how this affects cell signalling and responses to the environment. It is expected this will provide information about potential interventions to control fertility or to repair abnormal cells.