CRH Reproduction Seminar | Professor Shosei Yoshida
Prof Shosei Yoshida MD PhD, National Institute for Basic Biology (NIBB), Japan
Talk title: ‘Regulation of Spermatogonial Stem Cell Dynamics in the Testis’
Professor Yoshida has generated landmark discoveries on the biology of spermatogonial stem cells (SSCs) and pioneered intravital imaging approaches in the study of SSC topology and motion within seminiferous tubules. By combining lineage tracing studies with mathematical modelling, he has provided critical insight into fate dynamics of SSCs and documented the ability of progenitor populations to dedifferentiate to the SSC state to assist with germline regeneration. His studies have recently uncovered novel mechanisms that control SSC density within the testis.