Male Fertility Regulation Research Group
Research Group Head
Our overall aim is to identify how hormones control sperm production, or spermatogenesis. We have discovered that the reproductive and stimulating hormone and androgen regulate micro-RNAs in the testis, and are critical for the release of mature sperm. Our research continues to focus on how micro-RNAs control sperm release and how the blood-testis barrier works. We are also seeking to identify protein markers for development of a blood test for specific types of male infertility that will reduce the need for current invasive diagnostic techniques. This research is central to finding new mechanisms of contraception in men and understanding causes of male infertility.
Research Projects
- Proteomic discovery program in male reproduction
- Regulation of Sertoli Cell Junctions
- Regulation of sperm release
Research Group
Dr Liza O’Donnell, Research Scientist
Karen Chan, Research Support Staff