- Role: Postdoctoral ScientistGroup: Endometrial Stem Cell Biology
Dr Caitlin Filby is an experienced stem cell and molecular biologist and physiologist with expertise in development, stem cells, cancer and disease. She is highly trained in culture, isolation and identification of primary epithelial stem cells and has developed novel stem cell tools that will increase our understanding of the pathogenesis of endometriosis and will lead to novel precision diagnostic and therapeutic options for endometriosis.
Dr Caitlin Filby obtained her PhD at Monash University and completed postdoctoral training at Walter and Eliza Hall Institute of Medical Research and Murdoch Children’s Research Institute. Dr Filby joined the Hudson Institute of Medical Research to investigate the pathogenesis of endometriosis. Her long-term career goal is to be an internationally recognised endometriosis researcher who translates scientific discoveries into improved patient outcomes. She is passionate about endometriosis research and equal opportunities for women.
She is named investigator on a US Dept. of Defence-funded collaborative grant, has received her own funding from EndoFound and The CASS Foundation. In her new field she is recognised as an emerging leader through an oral presentation at World Congress on Endometriosis, invited oral presentation at the 2022 Society for Reproductive Investigation and 2019 Society for Reproductive Biology Endometriosis Satellite and selection for the inaugural VESKI Inspiring Women in STEM: Side By Side Program.
Students with good academic records and interest in endometriosis research projects may enquire for PhD and other research project opportunities.
Filby CE, Wyatt KA, Mortlock S, Cousins FL, McKinnon B, Tyson KE, Montgomery GW, Gargett CE (2021). Comparison of Organoids from Menstrual Fluid and Hormone-Treated Endometrium: Novel Tools for Gynecological Research. J Pers Med. 2021 Dec 6;11(12):1314. doi: 10.3390/jpm11121314. PMID: 34945786; PMCID: PMC8707872.
Wyatt KA*, Filby CE*, Suke S, Davies-Tuck M, Evans JE, Gargett CE (2021). Menstrual Fluid Endometrial Stem/Progenitor Cell and Plasma Supernatant Protein Content: Cyclical Variation and Indicative Range. Human Reproduction 2021. 36(8): 2215-2229.
Masuda H.*, Filby C.E.*, Schwab K.S.* Tan C.S.C. Tsaltas J., Weston G., Gargett C.E. (2021) Endometrial stem/progenitor cells in menstrual blood and peritoneal fluid of women with and without endometriosis. RBMO 2021 Jul;43(1):3-13. doi: 10.1016/j.rbmo.2021.04.008.
Ah-Cann C, Wimmer VC, Weeden CE, Marceaux C, Law CW, Galvis L, Filby CE, Liu J, Breslin K, Willson T, Ritchie ME, Blewitt ME, Asselin-Labat ML. (2021) A functional genetic screen identifies aurora kinase b as an essential regulator of Sox9-positive mouse embryonic lung progenitor cells. Development. 2021 Jul 1;148(13):dev199543. doi: 10.1242/dev.199543. Epub 2021 Jul 7. PMID: 34121118.
Filby CE, Rombauts L, Montgomery GW, Giudice LC, Gargett CE. (2020) Cellular Origins of Endometriosis: Towards Novel Diagnostics and Therapeutics. Semin Reprod Med. 2020 May;38(2-03):201-215. doi: 10.1055/s-0040-1713429. Epub 2020 Nov 11. PMID: 33176364
Lucciola R, Vrljicak P, Gurung S, Filby C, Darzi S, Muter J, Ott S, Brosens JJ, Gargett CE. (2020) Impact of Sustained Transforming Growth Factor-β Receptor Inhibition on Chromatin Accessibility and Gene Expression in Cultured Human Endometrial MSC. Front Cell Dev Biol. 2020 Sep 1;8:567610. doi: 10.3389/fcell.2020.567610. PMID: 32984350; PMCID: PMC7490520.
Asselin-Labat ML, Filby CE. (2012) Adult lung stem cells and their contribution to lung tumourigenesis. Open Biol. 2012 Aug;2(8):120094. doi: 10.1098/rsob.120094. PMID: 22977734; PMCID: PMC3438537.