Dr Erin McGillick from the Fetal and Neonatal Health Research Group at Hudson Institute

Dr Erin McGillick

Dr Erin McGillick is a NHMRC Peter Doherty Early Career Research Fellow in the Fetal and Neonatal Health research group at The Ritchie Centre, Hudson Institute of Medical Research and Adjunct Research Fellow in the Department of Obstetrics and Gynaecology at Monash University.

Dr McGillick’s research uses an integrative approach at the molecular and functional physiology level to understand how a compromised intrauterine environment affects lung growth and the transition from fetal to newborn life. Her research has discovered previously unrealised molecular mechanisms causing delayed lung development and subsequent predisposition to respiratory complications at birth in complicated pregnancies (gestational diabetes, maternal overnutrition, intrauterine growth restriction).

Dr McGillick’s current work using cutting edge pre-clinical models and state-of-the-art synchrotron X-ray imaging techniques is aimed at understanding mechanisms causing newborn cardiorespiratory dysfunction and identifying new/improved strategies to assist compromised babies successfully make the transition from fetal to newborn life. Dr McGillick’s research involves collaborations with physiologists, physicists and clinicians towards generating the necessary pre-clinical evidence that can be translated into future clinical trials to improve newborn cardiorespiratory outcomes.

Selected publications

  • Dekker J, Martherus T, Lopriore E, Giera M, McGillick EV, Hutten GJ, van Leuteren RW, van Kaam AH, Hooper SB, te Pas AB (2019) The effect of initial high versus low FiO2 on breathing effort in preterm infants at birth: A randomized controlled trial, Frontiers in Pediatrics 7(504)

  • Dekker J, Hooper SB, Croughan M, Crossley KJ, Wallace MJ, McGillick EV, DeKoninck PLJ, Thio M, Martherus M, Ruben G, Roehr CC, Cramer SJE, Flemmer A, Croton L, te Pas AB, Kitchen MJ (2019) Increasing respiratory drive with 100% oxygen during resuscitation of preterm rabbits at birth, Frontiers in Paediatrics 7(427)

  • Kashyap AJ, DeKoninck PL, Rodgers KA, Thio M, McGillick EV, Amberg BJ, Skinner SM, Moxham SM, Russo FM, Deprest JA, Hooper SB, Crossley KJ, Hodges RJ  (2019) Antenatal sildenafil treatment improves neonatal pulmonary hemodynamics and gas exchange in lambs with a diaphragmatic hernia, Ultrasound in obstetrics and gynaecology 54(4):506-516

  • McGillick EV, Davies I, Hooper SB, Kerr L, Thio, M, DeKoninck P, Yamaoka S, Hodges R, Rodgers K, Zahra V, Moxham A, Kashyap A, Crossley KJ 2019, Effect of lung hypoplasia on the cardiorespiratory transition in newborn lambs, The Journal of Applied Physiology; 127(2):568-578

  • Brouwer E, te Pas AB, Polglase GR, McGillick EV, Crossley KJ, Blank D, Yamaoka S, Gill A, Kluckow M, Hooper SB, (2019) Effect of spontaneous breathing on umbilical venous blood flow and placental transfusion during delayed cord clamping, Archives of Disease in Childhood: Fetal and Neoantal Edition; 105(1): 26-32

  • Amberg BJ, Hodges R, Kashyap AJ, Skinner S, Rodgers K, McGillick EV, Deprest J, Hooper SB, Crossley KJ, DeKoninck P, (2019) Physiological Effects of Partial Amniotic Carbon Dioxide Insufflation With Cold, Dry vs Heated, Humidified Gas in a Sheep Model, Ultrasound in Obstetrics & Gynaecology,53(3):340-347

  • Martherus T, Oberthuer A, Dekker J, Hooper SB, McGillick EV, Kribs A, Te Pas AB (2019) Supporting Breathing of Preterm Infants at Birth: A Narrative Review Arch Dis Child Fetal Neonatal Ed 2019, 104(1):F102-107