Dr Gabrielle Bradshaw, Alfie Chivers Research Fellow - funded by Robert Connor Dawes Foundation

Dr Gabrielle Bradshaw is a Postdoctoral Research Fellow focusing in paediatric brain cancer research. Specifically, Dr Bradshaw is working on Alfie’s Project, a two year project in memory of Alfie Chivers, generously funded by the Robert Connor Dawes Foundation. She is also affiliated with the Hudson Monash Paediatric Precision Medicine Program (HMPPM Program).

After completing her PhD in Genomics with Professor Lyn Griffiths at the Institute of Health and Biomedical Innovation at QUT, Dr Bradshaw joined the HMPPM Program in 2019.  Her current work on Alfie’s project involves performing functional interrogation of paediatric brain tumour pathway dependencies. Her research involves use of clinically relevant in vitro tumour models, such as patient derived cell lines, for development of stable Cas9-expressing cell lines for pooled CRISPR gRNA library screening. Computational and integrative analysis of functional and molecular data is undertaken, to enable the analysis of paediatric brain tumour dependencies.

Selected publications

  • Bradshaw G, Sutherland HG, Camilleri ET, Lea RA, Haupt LM, Griffiths LR (2015) Genetic and epigenetic variants in the MTHFR gene are not associated with non-Hodgkin lymphoma. Meta Gene 6:91-95.

  • Bradshaw G, Sutherland HG, Haupt LM, Griffiths LR (2016) Dysregulated microRNA expression profiles and potential cellular, circulating and polymorphic biomarkers in non-Hodgkin lymphoma. Genes (Basel) 7:130-149.

  • Bradshaw G, Lualhati RR, Albury CL, Maksemous N, Roos-Araujo D, Smith RA, Benton MC, Eccles DA, Lea RA, Sutherland HG, Haupt LM, Griffiths LR (2018) Exome sequencing diagnoses X-linked moesin-associated immunodeficiency in a primary immunodeficiency case. Front Immunol 9:420.

  • Bradshaw G, Haupt LM, Aquino EM, Lea RA, Sutherland HG, Griffiths LR (2019) Single nucleotide polymorphisms in MIR143 contribute to protection against non-Hodgkin lymphoma in Caucasian populations. Genes (Basel) 10:185-210.