Dr Heidi Bildsoe

After finishing her Master’s Degree at the University of Copenhagen, Dr Heidi Bildsoe worked at King’s College, London as a Research Assistant in Professor Simon Hughes’ Muscle Signalling Group.  She then undertook her PhD studies in 2008 with Professor Patrick Tam at the Children’s Medical Research Institute in Sydney investigating the function and downstream targets of the transcription factor Twist1 during craniofacial development.

In 2015 Dr. Bildsoe relocated to Melbourne to work as an EMBL Postdoctoral Research Fellow with Associate Professor Edwina McGlinn at ARMI (Monash University) elucidating genomic and epigenetic regulation of Hox gene expression during axial formation.

Dr. Bildsoe has recently joined Dr Patrick Western’s team at the Centre for Reproductive Health, Hudson Institute of Medical Research, to work on germ cells development and epigenetic inheritance.

Selected publications

  • Fan X, Loebel DAF, Bildsoe H, Wilkie EE, Qin J, Wang J,Tam PP, Loebel DAF (2016) Tissue interactions, cell signalling and transcriptional control in the cranial mesoderm during craniofacial development. AIMS Genetics.

  • Bildsoe H, Fan X, Wilkie EE, Ashoti A, Jones VJ, Power M, Qin J, Wang J,Tam PP, Loebel DAF (2016) Transcriptional targets of TWIST1 in the cranial mesoderm regulate cell-matrix interactions and mesenchyme maintenance. Dev Bio 418(1):189-203.

  • Loebel DAF, Hor AC, Bildsoe H, Tam PP (2014)  Timed deletion of Twist1 in the limb bud reveals age-specific impacts on autopod and zeugodpod patterning. PLoS One 9(6):e98945.

  • Bildsoe H, Loebel DAF, Hor A, Jones VJ, Braithwaite A, C, Chen YT, Behringer RR, Tam PP (2013) The mesenchymal architecture of the cranial mesoderm of mouse embryos is disrupted by the loss of Twist1 function. Dev Bio 374(2):295-307.

  • Loebel DAF, Hor A, Bildsoe H, Jones VJ, Chen YT, Behringer RR, Tam PP (2012) Regionalized Twist1 activity in the forelimb bud drives the Morphogenesis of the proximal and preaxial skeleton. Dev Bio 362: 132-40.

  • Bildsoe H, Loebel DAF, Jones VJ, Chen YT, Behringer RR, Tam PP (2009) Requirement for Twist1 in frontonasal and skull vault development in the mouse embryo. Dev Bio 331:176-88.

  • Henriquez JP, Webb A, Bence M, Bildsoe H, Sahores M, Hughes SM, Salinas PC (2008) Wnt signalling promotes AChR aggregation at the neuro-muscular synapse in collaboration with agrin. PNAS 105:18812-18817.

  • Franklin V, Bildsoe H, Tam PP (2007) Fate-mapping technique: grafting fluorescent cells into gastrula-stage mouse embryos at 7-7.5 days post-coitum. CSH Protocols pdb.prot4915.

  • Bildsoe H, Franklin V, Tam PP (2007) Fate-mapping technique: Using carbocyanine dyes for vital labeling of cells in gatrula-stage mouse embryos cultured in vitro. CSH Protocols pdb.prot, 4892.

  • Brack AS, Bildsoe H, Hughes SM (2005) Evidence that satellite cell decrement contributes to preferential decline in nuclear number from large fibres during murine age-related muscle atrophy. J Cell Sci 118: 4813-4821.

  • Li X*, Blagden CS*, Bildsoe H*, Bonnin MA, Duprez D, Hughes SM (2004) Hedgehog can drive terminal differentiation of amniote slow skeletal muscle. BMC Dev Biol 6;4:9.  (*Equal contribution)