Dr Karthika Radhakrishnan is a post-doctoral researcher working with Dr Catherine Carmichael in the Leukaemia Modelling and Therapeutic Discovery Research group, Centre for Cancer Research; and Professor Kate Loveland in the Testis Development and Germ Cell Biology Research group, Centre for Reproductive Health at Hudson Institute of Medical Research.

After completing her PhD in Reproductive Biology, Dr Radhakrishnan joined the Testis Development and Germ Cell Biology research group in 2018 to understand the role of TGF-β signalling pathway in testicular germ cell development. Her work highlights the role of nuclear transport protein, IPO5, in modulating TGF-β signalling pathway in the testicular cancer cells.

She joined the Leukaemia Modelling and Therapeutic Discovery research group in mid-2022, and her current research involves elucidating the molecular mechanism driving the development and pathogenesis of Acute Erythroid Leukaemia.

Selected publications

  • Micati DJ, Radhakrishnan K, Young JC, Rajpert-De Meyts E, Hime GR, Abud HE, Loveland KL (2020) Snail factors in testicular germ cell tumours and their regulation by the BMP4 signalling pathway. Andrology, 8(5):1456-1470.

  • Soumya A, Radhakrishnan K, Kumar PG (2018) DNA Methylation and Histone Modifications Associated with Male Germ Cell Differentiation. Journal of Endocrinology and Reproduction, 22(1):1-20.

  • Radhakrishnan K, Bhagya KP, Kumar AT, Devi AN, Sengottaiyan J, Kumar PG (2016) Autoimmune Regulator (AIRE) Is Expressed in Spermatogenic Cells, and It Altered the Expression of Several Nucleic-Acid-Binding and Cytoskeletal Proteins in Germ Cell 1 Spermatogonial (GC1-spg) Cells. Mol Cell Proteomics, 15(8):2686-2698.

  • Sree S, Radhakrishnan K, Indu S, Kumar PG (2014)  Dramatic changes in 67 miRNAs during initiation of first wave of spermatogenesis in Mus musculus testis: global regulatory insights generated by miRNA-mRNA network analysis.  Biol Reprod, 91(3):1-69.