- Role: Postdoctoral ScientistGroup: Amnion Cell Biology
Dr Mirja Krause is a postdoctoral researcher within the Amnion Cell Biology Group at Hudson Institute. She has expertise in multidisciplinary research encompassing the field of stem cell biology, process development and exosome biology.
Her research projects are focused on the understanding and characterisation of the secretome of amniotic cells to utilise its potential in possible medical applications. Dr Krause is involved in a clinical trial for stroke in a combined effort involving Hudson Institute, Monash University, Monash Health, and La Trobe University.
After completing her Master of Science degree in Biology at the Georg-August University Göttingen, Germany. Dr Krause worked for a biotechnology company in Finland before pursuing her PhD at the Technical University of Berlin, Germany in the field of Protein Engineering. In 2014 she was recruited to the Biocentre Oulu and the University of Oulu, Faculty of Biochemistry and Molecular Medicine. Her work focused on the secretome of the embryonic kidney and how the different cell types communicate during nephrogenesis. She employed state-of-the-art organoid techniques working with primary embryonic kidney cell lines.
In 2016, Dr Krause was recruited to The Ritchie Centre at Hudson Institute to join the Amnion Cell Biology group under the supervision of Dr Rebecca Lim. Dr Krause has a keen interest in translational and discovery research.
Krause M, Rak-Raszewska A, Naillat F, Saarela U, Schmidt C, Ronkainen V, Bart G, Ylä-Herttuala S, Vainio SJ. (2018) Exosomes as secondary inductive signals involved in kidney organogenesis. J Extracell Vesicles. 7(1): 1422675.
Tan JL, Lau SN, Leaw B, Nguyen HPT, Salamonsen LA, Saad MI, Chan ST, Zhu D, Krause M, Kim C, Sievert W, Wallace EM, Lim R. Amnion Epithelial Cell‐Derived Exosomes Restrict Lung Injury and Enhance Endogenous Lung Repair. (2018) Stem Cells Transl Med. 7(2): 180–196. doi: 10.1002/sctm.17-0185