Dr Ina Rudloff

Rudloff I*, Christie M, Deen NS, Ellisdon AM, Nold-Petry CA, Nold MF. (2026) Cytokine multimerization: when more is more and sometimes less. Nat Rev Immunol. 26(8):591-612.
* corresponding author

Rudloff I, Godsell J, Nold-Petry CA, Harris J, Hoi A, Morand EF, Nold MF. (2015) Interleukin-38 Exerts Antiinflammatory Functions and Is Associated With Disease Activity in Systemic Lupus Erythematosus. Arthritis Rheumatol. 67(12):3219-25.

Nold-Petry CA, Lo CY, Rudloff I, Elgass KD, Li S, Gantier MP, Lotz-Havla AS, Gersting SW, Cho SX, Lao JC, Ellisdon AM, Rotter BM, Azam T, Mangan NE, Rossello FJ, Whisstock JC, Bufler P, Garlanda C, Mantovani A, Dinarello CA, Nold (2015) IL-37 requires the receptors IL-18Ra and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction. Nat Immunol. 16(4):354-65.

Ellisdon AM, Nold-Petry CA, D’Andrea L, Cho SX, Lao JC, Rudloff I, Ngo D, Lo C, Soares da Costa T, Perugini MA, Conroy PJ, Whisstock JC, Nold MF. (2017) Homodimerization attenuates the anti-inflammatory activity of interleukin-37. Sci Immunol. 10;2(8).

Rudloff I, Cho SX, Lao JC, Ngo D, McKenzie M, Nold-Petry CA, Nold MF. (2017) Monocytes and dendritic cells are the primary source of interleukin 37 in human immune cells. J Leukoc Biol. 101(4):901-911.

Rudloff I, Ung HK, Dowling JK, Mansell A, D’Andrea L, Ellisdon AM, Whisstock JC, Berger PJ, Nold-Petry CA, Nold MF. (2020) Parsing the IL-37-mediated suppression of inflammasome function. Cells. 10;9(1).

Rudloff I*, Jarde T, Bachmann M, Elgass KD, Kerr G, Engel R, Richards E, Oliva K, Wilkins S, McMurrick PJ, Abud HE, Muehl H, Nold MF.  (2020) Molecular signature of interleukin-22 in colon carcinoma cells and organoid models. Transl Res. 216:1-22.
* corresponding author

Godsell J*, Rudloff I*, Kandane-Rathnayake R, Hoi A, Nold MF, Morand EF, Harris (2016) Clinical association of IL-10 and IL-37 in systemic lupus  rythematosus. Sci Rep. 6:34604.
* co-first authors

Bujotzek A, Tiefenthaler G, Lariviere L, D’Andrea L, Marquez EA, Rudloff I, Cho SX, Deen NS, Richter W, Regenass-Lechner F, Poehler A, Whisstock JC, Sydow Andersen J, Reiser X, Schuster S, Neubauer J, Hoepfl S, Richter K, Nold MF, Nold Petry CA, Schumacher F, Ellisdon AM. (2022) Protein engineering of a stable and potent anti-inflammatory IL-37-Fc fusion with enhanced therapeutic potential. Cell Chem Biol. 29(4):586-596.

Cho SX, Rudloff I, Lao JC, Pang MA, Goldberg R, Bui CB, McLean CA, Stock M, Klassert TE, Slevogt H, Mangan NE, Cheng W, Fischer D, Gfrörer S, Sandhu M, Ngo D, Bujotzek A, Lariviere L, Schumacher F, Tiefenthaler G, Beker F, Collins C, Kamlin O, König K, Malhotra A, Tan K, Theda C, Veldman A, Ellisdon AM, Whisstock JC, Berger PJ, Nold-Petry CA, Nold MF. (2020) Characterization of the Pathoimmunology of Necrotizing Enterocolitis Reveals Novel Therapeutic Opportunities. Nat Commun. 11(1):5794.

Rudloff I, Cho SX, Bui CB, McLean C, Veldman A, Berger PJ, Nold MF, Nold-Petry (2016) Refining anti-inflammatory therapy strategies for  bronchopulmonary dysplasia. J Cell Mol Med. 21(6):1128-1138.