Professor Patrick Western

Blucher RO, Lim RS, Ritchie ME, Western PS (2024) VEGF-dependent testicular vascularisation involves MEK1/2 signalling and the essential angiogenesis factors, SOX7 and SOX17. BMC Biology.  Accepted for publication 19 August 2024.

Oberin R, Petautschnig S, Jarred EG, Qu Z, Tsai T, Youngson NA, Pulsoni G, Bildsoe H, Truong TT, Fernando D, Blucher RO, van den Buuse M, Gardner DK, Sims, NA, Adelson DL, Western PS (2024) Fetal growth delay caused by loss of non-canonical imprinting is resolved late in pregnancy and culminates in offspring overgrowth. eLife. May 30:13:e81875.

Blucher RO, Lim RS, Jarred EG, Ritchie ME, Western PS (2023) FGF-independent MEK1/2 signalling in the developing foetal testis is essential for male germline differentiation in mice. BMC Biol. 2023 Dec 5;21(1):281.

Jarred EG, Qu Z, Tsai T, Oberin R, Petautschnig S, Bildsoe H, Pederson S, Zhang QH, Stringer JM, Carroll J, Gardner DK, Van den Buuse M, Sims NA, Gibson WT, Adelson DL, Western PS  (2022) Transient polycomb activity represses developmental genes in growing oocytes. Clin Epigenetics. 2022 Dec 21;14(1):183.

Prokopuk L, Jarred EG, Blücher RO, McLaughlin EA, Stringer JM, Western PS (2022) An essential role for Polycomb Repressive Complex 2 in the mouse ovary.  Reproduction. 2022 Feb 17;163(3):167-182.

Stringer JM, Western PS (2019) A step toward making human oocytes. Nat Biotechnol 37(1):24-25.

Jarred EG, Bildsoe H, Western PS (2018) Out of sight, out of mind? Germ cells and the potential impacts of epigenomic drugs. F1000Res Dec 21;7. pii:F1000 Faculty Rev-1967.

Stringer JM, Forster SC, Qu Z, Prokopuk L, O’Bryan MK, Gardner DK, White SJ, Adelson D, Western PS (2018) Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance. BMC Biol 16(1):104.

Prokopuk L, Stringer JM, White CR, Vossen RHAM, White SJ, Cohen ASA, Gibson WT, Western PS (2018) Loss of maternal EED results in postnatal overgrowth. Clin Epigenetics 10(1):95.

Prokopuk L, Hogg K, Western PS (2018) Pharmacological inhibition of EZH2 disrupts the female germline epigenome.  Clin Epigenetics March 4; 10:33.

Western PS (2018) Epigenomic drugs and the germline:  Collateral damage in the home of heritability? Mol Cell Endocrinol 468:121-133.

Prokopuk L, Stringer JM, Hogg K, Elgass KD, Western PS (2017) PRC2 is required for extensive reorganization of H3K27me3 during epigenetic reprogramming in mouse fetal germ cells. Epigenetics Chromatin Feb 20;10:7.

Gustin SE, Stringer JM, Hogg K, Sinclair AH, Western PS (2016) FGF9, activin and TGFβ promote testicular characteristics in an XX gonad organ culture model.  Reproduction 152(5):529-543.

Gustin SE, Hogg K, Stringer JM, Rastetter RH, Pelosi E, Miles DC, Sinclair AH, Wilhelm D, Western PS (2016) WNT/β-catenin and p27/FOXL2 differentially regulate supporting cell proliferation in the developing ovary. Dev Biol 412(2):250-260.

Hogg K, Western PS (2015) Refurbishing the germline epigenome:  Out with the old, in with the new. Semin Cell Dev Biol 45:104-113.

Hogg K, Western PS (2015) Differentiation of fetal male germline and gonadal progenitor cells is disrupted in organ cultures containing knockout serum replacement. Stem Cells Dev 24(24):2899-2911.

Prokopuk L, Western PS, Stringer JM (2015) Transgenerational epigenetic inheritance:  adaptation through the germline epigenome? Epigenomics 7(5):829-846.

Miles DC, Wakeling SI, Stringer JM, van den Bergen JA, Wilhelm D, Sinclair AH, Western PS (2013) Signaling through the TGF beta-activin receptors ALK4/5/7 regulates testis formation and male germ cell development. PLoS One 8:e54606.

Stringer JM, Barrand S, Western P (2013) Fine-tuning evolution: germ-line epigenetics and inheritance. Reproduction 146:R37-48.

Wakeling SI, Miles DC, Western PS (2013) Identifying disruptors of male germ cell development by small molecule screening in ex vivo gonad cultures. BMC Res Notes 6:168.

Google Scholar Citations: http://scholar.google.com.au/citations?user=igBeqKUAAAAJ