tab – research
CRE-AID brings together a collaborative team of scientists, whose skills and expertise encompass the complex molecular pathways of the innate immune response that are associated with autoinflammatory conditions.
Our team also includes clinicians and patient advocates, who understand the challenges of identifying and managing this underdiagnosed group of conditions, to support real-world impact and translation of this research.
Research aims
Our program goal is to determine the mechanistic details of the pathways that cause autoinflammatory disease, and translate these findings into improved diagnosis and treatment for patients both nationally – and world-wide. More specifically, our projects aim to:
- Implement novel biomarker detection methodology
- Validate gene variants of unknown significance
- Identify new pathways driving autoinflammation
- Develop more specifically targeted therapies
Research underway
Inflammasomopathies
Interferonopathies
Relopathies