Technology platforms and capabilities

Scientist at Hudson Institute working in the technology platforms and capabilities facility.

Our pursuit of excellence is underpinned by world-leading capabilities and expertise through our integrated network of Technology Platforms.

Natalia Sampaio In the lab of the RNAte Platform at Hudson Institute

Leveraging robotic automation in testing services enables high throughput applications for library screening or testing of different conditions, thereby aiding the optimisation of new product development. Using iPSC models can reduce the risk of clinical trials failure and has the potential to accelerate the development of new RNA and mRNA products in the manufacturing pipeline.

The RNAte platform is designed to address the need for testing the immunoreactivity of RNA-based products, especially in established human cell models. The platform places a high priority on human induced pluripotent stem cell (iPSC) models for sensitive and accurate detection of immune responses.

General enquiries  enquiry@rnate.com.au

Cell therapies image

Accredited Cell Therapy Processing and Cryopreservation Facility in Melbourne

Hudson Institute Cell Therapies (HICT) offers a purpose-built facility for the safe, efficient, and compliant processing and cryopreservation of human blood and tissue products—serving the needs of clinicians, researchers, and industry partners involved in cell and gene therapy. Designed to improve accessibility and streamline clinical workflows, the facility enables the processing of blood products outside the Melbourne CBD, supporting clinical trials both within the Monash Medical Centre Precinct and at other trial sites across Australia.

Operating within a PC2 and ISO 8 certified cleanroom environment, HICT houses a dedicated cryopreservation suite managed under ISO 15189 standards. The facility is accredited to receive, store, and distribute human cellular therapy products, providing essential support for multi-site clinical cell therapy trials and cell therapy services. With a strong focus on quality, safety, and accessibility, Hudson Institute Cell Therapies supports the advancement of cellular therapies through robust infrastructure and close integration with clinical care.

General enquiries CellTherapies@hudson.org.au

Flow Cytometry

FlowCore MHTP provides flow cytometry services to researchers within MHTP and the wider scientific community.

FlowCore MHTP provides flow cytometry services to researchers within MHTP and the wider scientific community.Download PDF Flowcore

Flow cytometry is a high-speed laser-based technology enabling users to generate multiparametric data about cell characteristics or particles of interest based upon fluorescent probes and markers. It is a powerful tool in many fields including immunology, stem cell science, cancer research, aquatic and plant biology.

The facility currently operates one high-speed cell sorter as well as one conventional and two spectral flow cytometers. FlowCore MHTP provides the following services on a fee-for-service model:

  • Cell sorting
  • Cell analysis
  • Training for independent use of cell analysers
  • Advice on experimental design and data analysis

Contact us

Michael Thomson | Platform Manager
t:+ 61 3 8572 2494
e: michael.thomson@hudson.org.au

Dr Svenja Loering | Senior Research Officer
e: svenja.loering@hudson.org.au

General enquiries
e: flowcoremhtp.enquiries@monash.edu

Histology involves the study of the microscopic anatomy of cells and tissues. Tissues are carefully processed, sectioned and stained revealing delicate morphological features that can indicate health or disease for research, education or clinical studies.

Histology flyer image for the technology platforms and capabilities facility.
The Histology Platform has two service models

  • A full ‘professional’ end-to-end service provided by specialist staff
  • A ‘do-it-yourself’ service providing access to laboratory facilities, specialist equipment and consumables.

In addition, the experienced Histology team can provide advice, training and research assistance in

  • Dissection
  • Cassetting
  • Processing – to resin or paraffin
  • Cutting – fresh, resin or paraffin sections
  • Staining and coverslipping -automated or manual
  • Immunohistochemistry – automated utilising the Dako Autostainer
  • Micro Tissue array slide supply – creation of micro tissue arrays to suit your needs. We can create the multi block and provide sections for use as control tissue
  • Slide scanning – Olympus VS120 for brightfield and fluorescent scanning

Contact us

Camilla Cohen | Monash Histology Platform Manager
Monash University
t: + 61 3 9905 2740
e: camilla.cohen@monash.edu

Angela Vais | MHP-MHTP Histology Node Senior Officer
Hudson Institute
t: +61 3 9594 7442
e: angela.vais@monash.edu
e: histology@hudson.org.au

The Hudson Genomics facility provides a comprehensive range of technologies to analyse DNA and RNA, determining its structure and function and its role in health and disease.

Scientist from Hudson Institute working in the technology platforms and capabilities facility.
We provide a broad range of specialist genomic services based upon a fee-for-service model including

Quantitative real-time PCR – 384well and BioMark HD Multiplex qPCR
Next Generation Sequencing
Single Cell Sequencing using the 10x Genomics Chromium
Spatial Sequencing using the 10x Genomic Visium CytAssist

General Enquiries
e: 
genomics@hudson.org.au

Dr Trevor Wilson | Scientific Manager
t: +61 3 8572 2818

Jodee Gould | NGS Specialist
t: +61 3 8572 246

Anh Vo | NGS Specialist
e: 
genomics@hudson.org.au

Cell therapies image

The Micro Imaging Facility specialises in optical, fluorescence 4D, live cell and statistical microscopy methodologies, as well as image and data informatics to understand cellular and molecular processes.

Microimaging flyer image for the technology platforms and capabilities facility.MMI-MHTP charges subsidised hourly rates to cover training and instrument access for internal users.

Micro Imaging provides

  • Experimental design and troubleshooting
  • Instrumentation
  • Training
  • Research collaboration
  • Project development.

Contact us

Dr Sarah Creed | Platform  Manager
t: +61 3 8572 2816
e: sarah.creed@hudson.org.au

Hudson Institute accesses world class specialist mass spectrometry and proteomic equipment and expertise though a subscription with the Bio21 Proteomics Facility.

The facility currently has the following mass spectrometers

  • 2 x Thermo NanoLC/ OrbiTrap Fusion Lumos
  • 2 x Thermo NanoLC/ Q Exactive Plus mass spectrometer
  • Thermo NanoLC/ OrbiTRAP ELITE ETD mass spectrometer
  • Thermo Exactive Focus
  • Agilent 6520 LC/ESI-TOF mass spectrometer
  • Waters Vion IMS QTOF mass spectrometer
  • Waters Synapt HDX G2-Si Ion mobility mass spectrometer
  • Shimadzu 9030 QTOF LCMSMS
  • 4 x Agilent HPLC systems for sample preparation.
  • 3 x Shimadzu Prep HPLC with UV and MS detection
  • Waters M Class HPLC for micro-purification

This equipment and downstream analysis can be used to perform common and more complex methods such as

  • In-solution protein identification and IP-MS identification
  • In-gel protein identification
  • Characterise intact recombinant proteins by mass
  • Confirm chemical synthesis
  • Identify phosphorylation sites
  • Immune-precipitation of protein complexes
  • Labelled and label-free quantitation
  • Stable Isotope Labelling by/with Amino acids in Cell culture
  • APEX biotin labelling
  • Hydrogen Deuterium Exchange

Contact us

Dr Daniel Garama
Proteomics Specialist
e: daniel.garama@hudson.org.au

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