Lung cancer occurs when cells divide in the lungs uncontrollably, causing tumours to grow. This can affect a patient’s breathing and the cancer can spread to other parts of the body.
Lung cancer is the leading cause of cancer deaths in the world and Australia.
What causes lung cancer?
What are the types of lung cancer?
What are lung cancer treatments?
Our lung cancer research
Hudson Institute researchers are working to understand how to prevent, detect and treat lung cancer.
Our teams are making significant progress in identifying an early detection test and new treatment targets for lung cancer patients.
Overcoming platinum resistant small cell lung cancer (SCLC)
Improved treatment. The majority of small cell lung cancer patients are diagnosed with advanced disease, which limits their treatment options to platinum-based chemotherapy. These patients typically respond well, but for a limited time before a drug resistant disease recurs. There is no effective second line therapy, and as a result more than 95 per cent of patients succumb to their disease. Dr Gough’s research is defining the mechanisms that drive platinum resistance to enable more durable responses to this key front-line agent. In addition, his team is identifying new therapies that can treat platinum resistant disease, which will improve the treatment arsenal. Dr. Gough’s laboratory uses combinations of patient derived material, resistant cell lines, pre-clinical mouse models of treatment naïve and platinum resistant disease, functional genomics, proteomics and drug screening technologies.
Re-engaging the immune system to kill SCLC
Targeting epigenetic dysregulation in lung cancer
Lung cancer drug and diagnostic under development
Breakthrough lung cancer drug
What drives the muscle-wasting caused by cancer?
Illuminating the role of ADAM17 in lung cancer
Inflammation and cancer
Lung cancer collaborators
- University of Melbourne
- Cancer Care Manitoba – Dr Neil Watkins
- Garvan Institute
- University of California San Francisco – Dr E. Alejandro Sweet-Cordero
- University of Kiel
- Monash University
- RMIT University
- Weizmann Institute of Science
Support for people with lung cancer
Hudson Institute scientists cannot provide medical advice.
Find out more about Lung cancer.
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