Centre Head
Hudson Institute of Medical Research is internationally recognised for its outstanding research into reproduction, which spans more than 40 years. The Centre for Reproductive Health’s current reproductive health research program is strongly based in both basic and translational science. Reproductive Health is now a key global challenge, with impacts of the environment and changes in societies strongly impacting not only on both male and female reproduction but also on the long-term health of their offspring. The latter detrimental changes are established both in the sperm and egg, and during early development of the conceptus.
With a rapidly increasing world population, the need for new contraceptive options has never been greater. Furthermore, translation of advances in reproductive sciences also impacts on cancer biology, animal food production, and conservation of endangered species. In addition, proteins involved in the regulation of reproduction also have wider actions influencing inflammation and tissue repair in a wide variety of organs.
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Well-deserved congratulations to Connie Malliaras and Tyra Fraser, CRH 2020 Honours students, for achieving outstanding first-class H1 Honours results in a very difficult year! These talented students showed great resilience and persistence in challenging times. L: Connie Malliaras (Supervisors: Prof Kate Loveland, Head, Testis Development and Germ Cell Biology and Ms Penny Whiley) R: Tyra Fraser (Supervisor: Dr Minni Anko, Head, Functional RNAomics) |
Penny Whiley, CRH PhD Student, awarded DGA Lecture Prize in the experimental field for the oral presentation ‘Activin A modulates the pace of germ cell development at the onset of spermatogenesis’. International Congress of Andrology (Digital), 5-9 December 2020. (Supervisors: Prof Kate Loveland, A/Prof Robin Hobbs, A/Prof Peter Stanton).
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Detection of immune cells on newborn mouse testis. “To study immunephysiology of testis during fetal development I used direct and indirect immunofluorescence technique for detecting macrophages, F4/80 marker (green colour) MHC class II positive cells (yellow colour) and laminin (pink colour) in interstitial and peritubular areas on day 0 mouse testis frozen section” – Samira Hosseini, CRH PhD Student. July 2020 |
Undifferentiated spermatogonia enriched for stem cell capacity from an adult mouse testis. Spermatogonial stem cells are essential for ongoing sperm production, without them males eventually become infertile. Immunofluorescence on adult mouse testis, SALL4 (red fluorescent signal) marks gonocytes, GFRA1 (green fluorescent signal) marks cells with a high stem cell potential, and DNA counterstained with DAPI (blue). Penny Whiley, CRH PhD Student. July 2020 |
Professor Kate Loveland receives International Scientist Award
Key areas of research
- Male Reproductive Health
- Male factor infertility
- Male reproductive cancer
- Immunobiology in male reproductive health
- Uterine Biology
- Disorders affecting female fertility
- Endometrial receptivity
- Reproductive Developmental Biology
- Offspring health
- Environmental exposures
- Molecular Biology of Reproduction
- Germline genetics and epigenetics
- RNA biology
Student Research Projects at Centre for Reproductive Health
Research Groups
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Endocrinology and Immunophysiology
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Endometrial Remodelling
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Functional RNAomics
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Germ Cell Development and Epigenetics
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Germline Stem Cell Biology
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Male Fertility Regulation
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Testis Development and Male Germ Cell Biology
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