Inflammation and cancer

Inflammatory cells

Inflammation and cancer

You are alive because of inflammation. It is your body’s natural response to infection or injury. In normal circumstances, inflammation eliminates foreign invaders (bacteria or viruses), damaged cells to heal wounds within hours or days.

However, this life-saving friend can also turn to foe. Chronic inflammation is linked to more than 50 per cent of all deaths worldwide and at least one in five cancers.

Inflammation – good or bad?

How does inflammation contribute to cancer?

What causes chronic inflammation?

Our research in inflammation and cancer

Hudson Institute scientists are studying how chronic inflammation contributes to the emergence of some deadly cancers, including pancreatic, lung and stomach cancer.

By identifying the mechanisms of our immune system that drive inflammation and cancer, we can better understand how inflammation is involved in tumour formation and growth. This knowledge will aid in the development of inflammation-targeting drugs that fight cancer progression and alleviate disease.

Inflammation and cancer

Professor Brendan Jenkins from the Cancer and Immune Signalling Research Group at Hudson Institute

Molecular. Genetic studies. Using a combined molecular biological and genetic approach coupled with human translational studies, the team is working on identifying the mechanisms by which key regulators of the innate immune system (e.g. pattern recognition receptors, inflammasomes, IL-6 family cytokines) drive inflammation-associated cancers (stomach, lung, pancreatic) and emphysema/chronic obstructive pulmonary disease (COPD).

Closing in on ovarian cancer therapy

RNA therapeutics for immunotherapy

Inflammation in cancer cells

Immune responses that dictate metastatic spread in breast cancer

A new therapeutic target for Helicobacter pylori-induced stomach cancer

Bacterial vesicles impact host cell functions and modulate inflammation

Illuminating the roles of STAT3 in health and disease

Inflammation and cancer collaborators

Support for people with inflammation and cancer

Hudson Institute scientists do not provide medical advice.
Find out more about inflammation and cancer.

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