Professor Euan Wallace AM, Carl Wood Clinical Professor

Professor Euan Wallace is Co-Head (Department of Obstetrics and Gynaecology) of The Ritchie Centre at Hudson Institute of Medical Research, and the Carl Wood Professor and Head of Department of Obstetrics and Gynaecology at Monash University. As Head of The Ritchie Centre (2010-2014) he brought together leading research groups in women’s health, fetal and neonatal physiology, infant and child health and stem cell biology to create a translational research centre. Together with Professor Stuart Hooper (Centre Executive Head) and Professor Nick Freezer (Co-Head, Paediatrics), Professor Wallace continues to build The Ritchie Centre to become one of the word’s leading research centres in women’s and children’s health. The centre is already the major component of the Women’s, Children’s, and Reproductive Health Theme of Monash Partners Academic Health Science Centre.

Professor Wallace’s own research focuses on basic and clinical aspects of pregnancy and pregnancy care. The team has an international reputation for its Down Syndrome screening research, the investigation of inhibins and activins in pregnancy and in fetal neuroprotection. More recently, the group has established research programs in novel therapies for preeclampsia and in ethnicity related pregnancy outcomes. The group is a world leader in amnion stem cell biology and their clinical translation.

Professor Wallace is also Director of Obstetric Services for Monash Health, overseeing a large clinical team at Monash Health’s three maternity sites (Monash Medical Centre, Dandenong Hospital and Casey Hospital).  His clinical interests are in high-risk pregnancy, including recurrent miscarriage, multiple pregnancy, hypertension, and fetal growth problems.

He sits on a number of State Government committees, including the Perinatal Services Advisory Committee and the Consultative Council of Obstetric and Paediatric Mortality and Morbidity. He also sits on committees for a number of grant funding authorities, such as NHMRC, and on several Institutional scientific advisory boards. Professor Wallace has more than 230 peer-reviewed publications relating to his research and an h-index of 39.

Selected publications

  • A complete list of publications can be found at Prof Wallace Publication List

    A selection of publications (2010-2014):

    Lim R, Acharya R, Delpachitra P, Hobson S, Sobey CG, Drummond GR, Wallace EM. Activin and NADPH-oxidase in preeclampsia: insights from in vitro and murine studies. Am J Obstet Gynecol. 2014; S0002-9378(14)00721-2.

  • Bhatt S, Alison B, Wallace EM, Crossley KJ, Gill AW, Kluckow M, te Pas AB, Morely CJ, Polglase GR, Hooper SB. Delaying cord clamping until ventilation onset improves cardiovascular function at birth in preterm lambs. J Physiol 2013; 591 (8): 2113-26.

  • Hodges RJ, Jenkin G, Hooper SB, Allison B, Lim R, Dickinson H, Miller SL, Vosdoganes P, Wallace EM. Human amnion epithelial cells reduce ventilation-induced preterm lung injury in fetal sheep. Am J Obstet Gyn 2012; 206 (5): 448.e8-15.

  • Murphy SV, Shiyun SC, Tan JL, Chan S, Lim R, Jenkin G, Wallace EM. Human amnion epithelial cells do not abrogate pulmonary fibrosis in mice with impaired macrophage function. Cell Transplant 2012; 21 (7): 1477-92.

  • Drysdale H, Ranasinha S, Kendall A, Knight M, Wallace EM. Ethnicity and the risk of late-pregnancy stillbirth. MJA 2012; 197 (5): 278-81.

  • Murphy SV, Lim R, Heraud P, Cholewa M, Le Gros M, de Jonge MD, Howard DL, Paterson D, McDonald C, Atala A, Jenkin G, Wallace EM. Human amnion epithelial cells induced to express functional cystic fibrosis transmembrane conductance regulator. PLoS One 2012; 7 (9): e46533.

  • Murphy S, Lim R, Dickinson H, Acharya R, Rosli S, Jenkin G, Wallace EM. Human amnion epithelial cells prevent bleomycin-induced lung injury and preserve lung function. Cell Transplant 2011; 20 (6): 909-23.

  • Vosdoganes P, Hodges RJ, Lim R, Westover AJ, Acharya RY, Wallace EM, Moss TJM. Human amnion epithelial cells as a treatment for inflammation-induced fetal lung injury in sheep. Am J Obstet Gynecol 2011; 205: 156.e26-33.

  • Moodley Y, Ilancheran S, Samuel C, Vaghjiani V, Atienza D, Williams ED, Jenkin G, Wallace EM, Trounson A, Manuelpillai U. Human amnion epithelial cell translation abrogates lung fibrosis and augments repair. Am J Resp Crit Care 2010; 182: 643-51.

  • Miller SL, Yawno T, Alers NO, Castillo-Melendez M, Supramaniam VG, VanZyl N, Sabaretnam T, Loose JM, Drummond GR, Walker DW, Jenkin G, Wallace EM. Antenatal antioxidant treatment with melatonin to decrease newborn neurodevelopmental deficits and brain injury caused by fetal growth restriction. J Pineal Res. 2014; 56 (3): 283-94.