Obstructive lung diseases such as asthma and chronic obstructive pulmonary disease (COPD) affect more than a third of all Australians. Acute flares, caused by virus infections, often result in disability and sometimes death. My research aims to prevent this by enhancing immunity and designing new treatments.
Biography
A respiratory physician and scientist, Professor Philip Bardin’s research is focused on asthma and COPD and understanding how disease flares can be better understood and prevented. His goal is to find the key mechanisms for disease flares in asthma and COPD and use this knowledge to develop novel therapeutic approaches to prevent these devastating events.
With collaborators, Prof Bardin provided the first evidence that virus infections cause flares of asthma and COPD. Further research showed that immune responses are reduced in asthma and COPD leading to more severe illness. His latest research demonstrated that this problem can be mitigated by novel treatments.
Prof Bardin is an international authority in the field of asthma and COPD and a frequent invited speaker at global meetings. He has authored more than 200 peer-reviewed publications and has an H-Index of 49.
Over 20 years Prof Bardin has received more than $7M in grant funding from National government agencies (NHMRC), as well as from philanthropic funding bodies such as the National Asthma Council and Thoracic Society of Australia and New Zealand.
Prof Bardin is Professor and Director of Lung and Sleep Medicine Monash University and Hospital, Melbourne. Under his leadership over the last 13 years the clinical Department has more than tripled in size providing services to people with lung and sleep disorders. He is a practising clinician and supervises medical services at Lung and Sleep Medicine.
Laboratory research projects
- TGF-Beta laboratory studies using in vitro and murine studies.
- Effects of steroids in asthma/ chronic obstructive pulmonary disease (COPD). These studies examine new treatments for asthma/ COPD in mouse models.
- Human metapneumovirus (hMPV) studies in vitro. This is an important new virus and these studies examine its activity in asthma and COPD models.
- Extracellular traps in health and disease (with A/Prof Paul King).
Clinical research projects
- COPD studies focus on exacerbations, diagnostic imaging, cardiac morbidities, new treatments and rehabilitation.
- Asthma studies evaluate severe asthma, vocal cord dysfunction and new treatments.
- Lung infection studies are focused on disease mechanisms in bronchiectasis, cystic fibrosis, COPD and pneumonia.
Education
Awards and fellowships
Affiliations
Publication highlights
