Perinatal Inflammation and Neurophysiology

Too much inflammation is a major cause of damage to the fetal and newborn brain that can lead to neurodevelopmental disorders, such as cerebral palsy. We focus on understanding how inflammation during pregnancy or shortly after birth impairs brain cell development and function, and study how anti-inflammatory interventions could improve brain development using a multidisciplinary approach that includes fundamental neuroscience, neurophysiology, medical imaging, and patient samples.

Through collaborative partnerships with clinical experts, academia and industry, we are discovering new and improved drug targets for the treatment of perinatal brain injury and developing physiological biomarkers and imaging technology to improve brain injury detection for improved treatment outcomes.

Research projects

How do systemic and nueroimmune activation trigger perinatal brain injury?

Optimising interleukin-1 receptor antagonist for neonatal neuroprotection

Developing new anti-cytokine therapies for perinatal neuroprotection

Improving brain injury detection using advanced magnetic resonance imaging and phase contrast computed tomography

Identifying brain injury biomarkers using neonatal electroencephalography

Brain or brawn? Is creatine and effective intervention for neonatal neuroprotection

Research Group