Dr Shayanti Mukherjee

Dr Shayanti Mukherjee is a Science and Industry Endowment Fund (SIEF) John Stocker postdoctoral Fellow in the Women’s health theme at The Ritchie Centre, Hudson Institute of Medical Research. She completed her PhD at the National University of Singapore in 2013 where her work contributed to the growing body of nanobiomaterial research in repair and regeneration of infarcted myocardium.

Her current research investigates the evaluation of foreign body response to cell-based biomaterial constructs using Solution electrospinning, 3D Printing, Melt electrospinning and stem cell bioprinting for pelvic floor reconstruction surgeries. Using her inter-disciplinary research experience across academia and industry. Dr Mukherjee has a strong interest in accelerating the clinical translation of stem cell-based POP surgical constructs to improve the quality of life of millions of women worldwide.

Students interested in multip-disciplinary tissue engineering and nanomaterials projects may enquire for PhD and other research project opportunities. 

Selected publications

  • Paul K, Darzi S, McPhee G, Del Borgo MP, Werkmeister JA, Gargett CE, Mukherjee S (2019) 3D bioprinted endometrial stem cells on melt electrospun poly ε-caprolactone mesh for pelvic floor application promote anti-inflammatory responses in mice. Acta Biomaterialia S1742-7061(19)30550-1. 

  • Mukherjee SDarzi S, Troung Y, Kadam V, Rosamilia A, Werkmeister J and Gargett C (2019) Blended Nanostructured Degradable Mesh with Endometrial Mesenchymal Stem Cells Promotes Tissue Integration and Anti-Inflammatory Response in Vivo for Pelvic Floor Application. Biomacromolecules 20 (1), pp 454–468.

  • Emmerson S, Mukherjee S, Melendez J, Cousins F, Edwards SL, Karjalainen P, Ng M, Tan, KS, Darzi S, Bhakoo K, Rosamilia A , Werkmeister JA, Gargett CE (2019) Composite mesh design for delivery of autologous mesenchymal stem cells influences mesh integration, exposure and biocompatibility in an ovine model of pelvic organ prolapse. Biomaterials.

  • Mukherjee S, Darzi S, Paul K, Werkmeister JA, Gargett CE (2019) Mesenchymal stem cell-based bioengineered constructs: foreign body response, cross-talk with macrophages and impact of biomaterial design strategies for pelvic floor disorders. Interface Focus 6;9(4):20180089

  • Parkinson LA, Rosamilia A, Mukherjee S, Papageorgiou AW, Melendez-Munoz J, Werkmeister JA, Gargett CE, Arkwright JW (2019) A fiber-optic sensor-based device for the measurement of vaginal integrity in women.  Neurourol Urodyn.

  • S Darzi, J Deane, C Nold, S Edwards, D Gough, S Mukherjee, S Gurung, K Tan, A Vashi, J Werkmeister, and C Gargett (2018) Endometrial Mesenchymal Stem/Stromal Cells Modulate the Macrophage Response to Implanted Polyamide/Gelatin Composite Mesh in Immunocompromised and Immunocompetent Mice. Scientific Reports 8, Article number: 6554 (Q1)

  • C Gargett, S Gurung, S Darzi, J Werkmeister and S Mukherjee (2019) Tissue engineering approaches for treating pelvic organ prolapse using a novel source of stem/stromal cells and new materials. Current Opinion in Urology.

  • H Liu, S Mukherjee, J Kan, Y Liu, S Ramakrishna (2018) Recent studies on electrospinning preparation of patterned, core-shell and aligned scaffolds. Journal of Applied Polymer Science 135 (31), 46570.(Q2)

  • Kadam, Y Truong, C Easton, S Mukherjee, L Wang, R Padhye, I Kyratzis (2018) Electrospun Polyacrylonitrile/β–Cyclodextrin Composite Nanofiber Membranes for Simultaneous Air filtration and Gas adsorption. ACS Applied Nano Materials 1 (8), 4268-4277.